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DNA Fingerprinting Activity

Introduction to DNA Fingerprinting Activity

$3.99

Use a paper-based model to learn more about DNA Fingerprinting and the use of DNA in forensics.

Grades 7 and Up

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So much fun! This DNA fingerprinting activity is simplified specifically for middle school!

In this activity, students will:

  • Read a silly (not scary) murder mystery. The scene is set for students to figure out who killed Mr. Henry Lord Whippleton. There are two suspects… and one of their DNA fingerprints will match the DNA found at the crime scene!
  • Get an introduction to DNA fingerprinting with a 1-page introduction and a tiny bit of practice.
  • “Process” the two suspects’ DNA (involving cutting and pasting paper DNA strips) to make a DNA fingerprint for each suspect.
  • Compare the DNA fingerprints they have generated to the one found at the crime scene. Mystery solved!

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Teacher Notes:

  • Generally, with time for introduction and discussion, this activity takes 2 class periods.
  • Please note: This DNA fingerprinting activity is NOT editable.
  • NGSS Science & Engineering Practice: Developing and using models
  • Answer key provided.
  • Check out more resources in the DNA and heredity section of our shop!

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As a first year teacher, this is PERFECT! I don't have to waste time overthinking my wording on questions I've designed or chosen. I don't have to worry about covering all the standards. I don't have to worry about being biased, and it's great practice for my students to practice wording they'll find on standardized testing. This has been just amazing. 
Nathalie Y.
Amazing, high-quality, real-world applications. I love the station set up to get students moving around and collaborating with each other. Students are able to practice analyzing graphs, which is a huge part of their end-of-year state test, using a variety of charts, tables, graphs, and images. Love it!  
Chloe G.
It's always wonderful when you find a resource that is ready to go and aligns with the lesson perfectly, and this one does just that.
Rachel J.
GREAT resource!! Students were way more engaged with this format than with the typical 'packet' you find elsewhere for evidences. Short, sweet, to the point to cover all the content and allowed for more student-led discovery. My students enjoyed :)  
Betsy T.
I work at a school where the majority of the students are Latino. They were very ecstatic to learn about what contribution Latino's made to the Science community. I could see the awe and proudness on their faces.
Rana B.
 This bundle was very helpful as I revised my Climate unit. I used each of the resources, and my students' feedback was overwhelmingly positive. These are "keepers"!
Karen E.
This is an excellent resource. Lots of interesting info about zebra mussels, but the graphing activity is what makes it so great. Fantastic thoughtful questions about the graph that make the students analyze and predict. Loved it!
Ashley K.
Beautiful, well-researched lesson with many options and very little prep time required!  I found this was an EXCELLENT activity and students were very engaged!  Well done!   
Hope B.
The lab was one of the favorite activities of the year. Everything in this packet was aligned to the standards and worked perfectly. Kids loved it and I was so thankful to find such engaging activities. Thank you!  
Kristy S.
This is a great resource!  This resource was so thorough & comprehensive and was easy to implement with my limited resources and space, which was a huge plus for me! It was also super engaging for students to review cellular respiration. I'll definitely use this again and again!  
Meredith D.
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