DNA and Chromosomes Reading & Worksheet

This DNA and chromosomes reading passage and worksheet introduces students to the structure of DNA, what genes are, and how chromosomes store DNA. Perfect for the middle school level!

Includes both PRINT and GOOGLE SLIDES options to assign!

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In this activity, students will:

  • READ an article about the structure of DNA, genes, chromosomes, and karyotypes. All information is at an introductory level.
  • DEFINE key terms using context clues from the reading.
  • ANSWER text-dependent questions. All answers come from the text, so no prior knowledge is required!

The reading covers the following topics:

  • DNA basics – The genetic instruction molecule found in all living things
  • DNA structure – Double helix, made of nucleotides, four bases (A, T, G, C)
  • Genes – Specific DNA sections that code for traits and proteins
  • Chromosomes – Long DNA molecules are packaged and organized in cells
  • Human chromosomes – 46 total (23 pairs), including sex chromosomes
  • Karyotypes – Chromosome maps used to detect genetic abnormalities

Teacher Notes:

  • Includes answer key.
  • Please note that this DNA & Chromosomes Reading is not editable.
  • GO PAPERLESS! Use the included digital Google Slides option to assign!
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  • Get everything you need to teach DNA & chromosomes in my DNA UNIT!

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Grade Levels: 6, 7, 8, 9, 10 NGSS Standard: MS-LS3-1