Cell Organelles Activity: Observe Permeability of Cell Membranes

This middle school lab investigates the question “Is a cell membrane permeable?” using easy and cheap supermarket supplies!

In this activity, students will:

• Remove the shell of a chicken egg by soaking it in vinegar for 2 days. This creates a model of a cell that can be used to test the permeability of the cell membrane.
• Measure the mass and circumference of the eggs.
• Place the egg in 3 different liquids (sugar water, tap water, and saltwater).
• After the eggs have soaked, they measure the change in mass and circumference of each egg.
• Answer questions in an analysis section, including a claims/evidence/reasoning grid.

This procedure is sometimes used to discuss osmosis/diffusion and hypertonic/hypotonic solutions, but this one DOES NOT mention these concepts. This lab focuses on the permeability of the membrane in general.

Teacher Notes:

• Check out our Cells and Organelles Test.
• Answer key included.
• Please note that this resource is not editable.
• A printable tape measure is included in the download.
• NGSS Standard: MS-LS1-2
• NGSS Science & Engineering Practice: Developing and using models; Planning and carrying out investigations; Engaging in argument from evidence
• Check out more resources in the cells and organelles section of our shop!